HuagongsheHuagongshe Chemistry Print Report · For research reference only
Methyl iodide → HCID 67130990, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Methyl iodide | HCID 6328 | — |
| Reactant | Potassium Carbonate | HCID 11430 | — |
| Reactant | 4-[4-(3-Cyanophenyl)-2,5-dioxo-4-[(2-propenyloxy)methyl]imidazolidin-1-yl]-2-trifluoromethylbenzonitrile | HCID 67131010 | — |
| Solvent | Dimethylformamide | HCID 6228 | — |
| Product | HCID 67130990 | HCID 67130990 | — |
Reaction Steps
To a solution of 358 mg of 4-[4-(3-cyanophenyl)-2,5-dioxo-4-[(2-propenyloxy)methyl]imidazolidin-1-yl]-2-trifluoromethylbenzonitrile in DMF (1.5 mL) 135 mg of potassium carbonate and 101 μL of methyl iodide are added. The mixture is stirred during the night at room temperature, evaporated, washed with brine, extracted with ethyl acetate, dried over magnesium sulfate and concentrated to give the desired compound.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08383608B2 |
| Source dataset | uspto-grants-2013_02 |
| ORD ID | ord-bb3dc22d873548589f755927db058649 |
| Source note | uspto-grants-2013_02 |