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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 389918Generated: October 26, 2026

alpha-Cyclopentylmandelic acid → (R/S)-(2-Cyclopentyl-2-hydroxy-2-phenyl-acetoxy)-1-methyl-1-(pyrazin-2-yl-carbamoylmethyl)-pyrrolidinium bromide

https://huagongshe.com/reaction/389918

Reaction equation

Participants

RoleNameHCIDCharge
Reactantalpha-Cyclopentylmandelic acidHCID 98283—
ReactantHCID 131730243HCID 131730243—
Product(R/S)-(2-Cyclopentyl-2-hydroxy-2-phenyl-acetoxy)-1-methyl-1-(pyrazin-2-yl-carbamoylmethyl)-pyrrolidinium bromideHCID 131730251—

Reaction Steps

This compound is prepared by an analogous method to (1R/S,3R)-3-((R/S)-(2-cyclohexyl-2-hydroxy-2-phenyl-acetoxy)-1-methyl-1-(pyrazin-2-ylcarbamoylmethyl)-pyrrolidinium bromide (Example 1) by replacing cyclohexyl-hydroxy-phenyl-acetic acid with cyclopentyl-mandelic acid.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08383625B2
Source datasetuspto-grants-2013_02
ORD IDord-eda736cd8bf04a7e97993ecd9f2ae75f
Source noteuspto-grants-2013_02