HuagongsheHuagongshe Chemistry Print Report · For research reference only
alpha-Cyclopentylmandelic acid → (R/S)-(2-Cyclopentyl-2-hydroxy-2-phenyl-acetoxy)-1-methyl-1-(pyridazin-3-yl-carbamoylmethyl)-pyrrolidinium bromide
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | alpha-Cyclopentylmandelic acid | HCID 98283 | — |
| Reactant | (R/S)-(2-Cyclohexyl-2-hydroxy-2-phenyl-acetoxy)-1-methyl-1-(pyridazin-3-yl-carbamoylmethyl)-pyrrolidinium bromide | HCID 131730249 | — |
| Product | (R/S)-(2-Cyclopentyl-2-hydroxy-2-phenyl-acetoxy)-1-methyl-1-(pyridazin-3-yl-carbamoylmethyl)-pyrrolidinium bromide | HCID 131730255 | — |
Reaction Steps
This compound is prepared by an analogous method to (1R/S,3R)-3-((R/S)-(2-cyclohexyl-2-hydroxy-2-phenyl-acetoxy)-1-methyl-1-(pyridazin-3-ylcarbamoylmethyl)-pyrrolidinium bromide (Example 3) by replacing cyclohexyl-hydroxy-phenyl-acetic acid with cyclopentyl-mandelic acid.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08383625B2 |
| Source dataset | uspto-grants-2013_02 |
| ORD ID | ord-9ea769a3342a4866a598bccfd33fce4f |
| Source note | uspto-grants-2013_02 |