Potassium Carbonate → 3-amino-1-[{4-(2,4,6-trimethylbenzyl)piperazin-1-yl}propanoyl]-6-N-(p-tolyl)-4,5,6,7-tetrahydro-1-H-pyrazolo[3,4-c]pyridin-7-one

Participants

Reaction Steps

A target compound (130.2 mg, 0.253 mmol, 56.7%) was yielded as yellow solid in the same manner as Example 1 by reacting 3-amino-5,6-dihydro-6-N-(p-tolyl)-1H-pyrazolo[3,4-c]pyridin-7(4H)-one (108.2 mg, 0.446 mmol) with potassium carbonate (92.4 mg, 0.669 mmol) and 1-{4-(2,4,6-trimethylbenzyl)piperazin-1-yl}-3-chloropropan-1-one (151.3 mg, 0.490 mmol).

Provenance & Evidence