Potassium Carbonate → 3-amino-1-[{4-(4-t-butylbenzyl)piperazin-1-yl}propanoyl]-6-N-(p-tolyl)-4,5,6,7-tetrahydro-1H-pyrazolo[3,4-c]pyridin-7-one

Participants

Reaction Steps

A target compound (109.8 mg, 0.207 mmol, 50.4%) was yielded as yellow solid in the same manner as Example 1 by reacting 3-amino-5,6-dihydro-6-N-(p-tolyl)-1H-pyrazolo[3,4-c]pyridin-7(4H)-one (100 mg, 0.412 mmol) with potassium carbonate (85.4 mg, 0.618 mmol) and 1-{4-(4-t-butylbenzyl)piperazin-1-yl}-3-chloropropan-1-one (146.2 mg, 0.453 mmol).

Provenance & Evidence