Potassium Carbonate → 3-amino-1-[{4-(2,3,4-trimethoxybenzyl)piperazin-1-yl}propanoyl]-6-N-(p-tolyl)-4,5,6,7-tetrahydro-1H-pyrazolo[3,4-c]pyridin-7-one

Participants

Reaction Steps

A target compound (158.4 mg, 0.281 mmol, 53.8%) was yielded as white solid in the same manner as Example 1 by reacting 3-amino-5,6-dihydro-6-N-(p-tolyl)-1H-pyrazolo[3,4-c]pyridin-7(4H)-one (126.8 mg, 0.523 mmol) with potassium carbonate (108.3 mg, 0.784 mmol) and 1-{4-(2,3,4-trimethoxybenzyl)piperazin-1-yl}-3-chloropropan-1-one (205.1 mg, 0.575 mmol).

Provenance & Evidence