Potassium Carbonate → 3-amino-1-[{4-(2,3,4-trimethoxybenzyl)piperazin-1-yl}propanoyl]-6-N-(p-methoxyphenyl)-4,5,6,7-tetrahydro-1H-pyrazolo[3,4-c]pyridin-7-one

Participants

Reaction Steps

A target compound (136.1 mg, 0.235 mmol, 46.8%) was yielded as white solid in the same manner as Example 1 by reacting 3-amino-5,6-dihydro-6-N-(4-methoxyphenyl)-1H-pyrazolo[3,4-c]pyridin-7(4H)-one (129.8 mg, 0.502 mmol) with potassium carbonate (104.0 mg, 0.753 mmol) and 1-{4-(2,3,4-trimethoxybenzyl)piperazin-1-yl}-3-chloropropan-1-one (196.9 mg, 0.552 mmol).

Provenance & Evidence