HuagongsheHuagongshe Chemistry Print Report · For research reference only
Potassium Carbonate → 3-amino-1-[{4-(2,4,6-trimethylbenzyl)piperazin-1-yl}propanoyl]-6-N-phenyl-4,5,6,7-tetrahydropyrazolo[3,4-c]pyridin-7-one
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Potassium Carbonate | HCID 11430 | — |
| Reactant | 1-{4-(2,4,6-Trimethylbenzyl)piperazin-1-yl}-3-chloropropan-1-one | HCID 67996994 | — |
| Reactant | 3-amino-5,6-dihydro-6-phenyl-1H-pyrazolo[3,4-c]pyridin-7(4H)-one | HCID 67997073 | — |
| Product | 3-amino-1-[{4-(2,4,6-trimethylbenzyl)piperazin-1-yl}propanoyl]-6-N-phenyl-4,5,6,7-tetrahydropyrazolo[3,4-c]pyridin-7-one | HCID 67996974 | — |
Reaction Steps
A target compound (92.7 mg, 0.185 mmol, 35.3%) was yielded in the same manner as Example 1 by reacting 3-amino-5,6-dihydro-6-phenyl-1H-pyrazolo[3,4-c]pyridin-7(4H)-one (120 mg, 0.525 mmol) with potassium carbonate (108.7 mg, 0.787 mmol) and 3-chloro-1-{4-(2,4,6-trimethylbenzyl)piperazin-1-yl}propan-1-one (178.2 mg, 0.577 mmol).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08383631B2 |
| Source dataset | uspto-grants-2013_02 |
| ORD ID | ord-15b1118ad95d40c9bac6063b0311681f |
| Source note | uspto-grants-2013_02 |