HuagongsheHuagongshe Chemistry Print Report · For research reference only
Potassium Carbonate → 3-amino-1-[{4-(4-methoxyphenyl)piperazin-1-yl}propanoyl]-6-N-{p-(dimethylamino)phenyl}-4,5,6,7-tetrahydro-1H-pyrazolo[3,4-c]pyridin-7-one
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Potassium Carbonate | HCID 11430 | — |
| Reactant | 3-Chloro-1-[4-(4-methoxyphenyl)piperazin-1-yl]propan-1-one | HCID 20113708 | — |
| Reactant | 3-amino-6-N-(4-(dimethylamino)phenyl)-5,6-dihydro-1H-pyrazolo[3,4-c]pyridin-7(4H)-one | HCID 67997318 | — |
| Product | 3-amino-1-[{4-(4-methoxyphenyl)piperazin-1-yl}propanoyl]-6-N-{p-(dimethylamino)phenyl}-4,5,6,7-tetrahydro-1H-pyrazolo[3,4-c]pyridin-7-one | HCID 67997013 | — |
Reaction Steps
A target compound (22.2 mg, 0.043 mmol, 11.1%) was yielded in the same manner as Example 1 by reacting 3-amino-6-N-(4-(dimethylamino)phenyl)-5,6-dihydro-1H-pyrazolo[3,4-c]pyridin-7(4H)-one (105 mg, 0.387 mmol) with potassium carbonate (80.1 mg, 0.580 mmol) and 3-chloro-1-{4-(4-methoxyphenyl)piperazin-1-yl}propan-1-one (120.1 mg, 0.425 mmol).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08383631B2 |
| Source dataset | uspto-grants-2013_02 |
| ORD ID | ord-62a75fbc386342f880521d2f8adbb8af |
| Source note | uspto-grants-2013_02 |