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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 390027Generated: October 30, 2026

Potassium Carbonate → 3-amino-1-[{4-(4-methoxyphenyl)piperazin-1-yl}propanoyl]-6-N-{(furan-2-yl)methyl}-4,5,6,7-tetrahydropyrazolo[3,4-c]pyridin-7-one

https://huagongshe.com/reaction/390027

Reaction equation

Participants

RoleNameHCIDCharge
ReactantPotassium CarbonateHCID 11430—
Reactant3-Chloro-1-[4-(4-methoxyphenyl)piperazin-1-yl]propan-1-oneHCID 20113708—
Reactant3-amino-6-N-((furan-2-yl)methyl)-5,6-dihydro-1H-pyrazolo[3,4-c]pyridin-7(4H)-oneHCID 67996981—
Product3-amino-1-[{4-(4-methoxyphenyl)piperazin-1-yl}propanoyl]-6-N-{(furan-2-yl)methyl}-4,5,6,7-tetrahydropyrazolo[3,4-c]pyridin-7-oneHCID 67997071—

Reaction Steps

A target compound (191.5 mg, 0.400 mmol, 93.1%) was yielded as solid in the same manner as Example 1 by reacting 3-amino-6-N-((furan-2-yl)methyl)-5,6-dihydro-1H-pyrazolo[3,4-c]pyridin-7(4H)-one (100 mg, 0.430 mmol) with potassium carbonate (89.1 mg, 0.645 mmol) and 3-chloro-1-{4-(4-methoxyphenyl)piperazin-1-yl}propan-1-one (133.7 mg, 0.473 mmol).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08383631B2
Source datasetuspto-grants-2013_02
ORD IDord-72486818d03e4bb69111471283c2554f
Source noteuspto-grants-2013_02