Potassium Carbonate → 3-amino-1-[{4-(4-trifluoromethylphenyl)piperazin-1-yl}propanoyl]-6-N-(p-tolyl)-4,5,6,7-tetrahydro-1H-pyrazolo[3,4-c]pyridin-7-one

Participants

Reaction Steps

A target compound (176.3 mg, 0.334 mmol, 85.4%) was yielded as solid in the same manner as Example 1 by reacting 3-amino-5,6-dihydro-6-N-(p-tolyl)-1H-pyrazolo[3,4-c]pyridin-7(4H)-one (95 mg, 0.392 mmol) with potassium carbonate (81.2 mg, 0.588 mmol) and 3-chloro-1-[4-{4-(trifluoromethyl)phenyl}piperazin-1-yl]propan-1-one (138.2 mg, 0.431 mmol).

Provenance & Evidence