HuagongsheHuagongshe Chemistry Print Report · For research reference only
Potassium Carbonate → 3-amino-1-[{4-(4-t-butylphenyl)piperazin-1-yl}propanoyl]-6-N-(p-tolyl)-4,5,6,7-tetrahydro-1H-pyrazolo[3,4-c]pyridin-7-one
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Potassium Carbonate | HCID 11430 | — |
| Reactant | 3-amino-5,6-dihydro-6-p-tolyl-1H-pyrazolo[3,4-c]pyridin-7(4H)-one | HCID 67996997 | — |
| Reactant | 1-(4-(4-t-Butylphenyl)piperazin-1-yl)-3-chloropropan-1-one | HCID 67997037 | — |
| Product | 3-amino-1-[{4-(4-t-butylphenyl)piperazin-1-yl}propanoyl]-6-N-(p-tolyl)-4,5,6,7-tetrahydro-1H-pyrazolo[3,4-c]pyridin-7-one | HCID 67997059 | — |
Reaction Steps
A target compound (173.3 mg, 0.336 mmol, 86.8%) was yielded as solid in the same manner as Example 1 by reacting 3-amino-5,6-dihydro-6-N-(p-tolyl)-1H-pyrazolo[3,4-c]pyridin-7(4H)-one (94 mg, 0.388 mmol) with potassium carbonate (80.4 mg, 0.582 mmol) and 1-{4-(4-t-butylphenyl)piperazin-1-yl}-3-chloropropan-1-one (131.5 mg, 0.426 mmol).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08383631B2 |
| Source dataset | uspto-grants-2013_02 |
| ORD ID | ord-bba00dd395734593b79c1e50ca85946c |
| Source note | uspto-grants-2013_02 |