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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 390058Generated: October 31, 2026

n-(3-Aminophenyl)pyrrolidine-1-carboxamide → N-(3-{[5-cyano-6-methyl-2-(methylthio)-4-pyrimidinyl]amino}phenyl)-1-pyrrolidinecarboxamide

https://huagongshe.com/reaction/390058

Reaction equation

Participants

RoleNameHCIDCharge
Reactantn-(3-Aminophenyl)pyrrolidine-1-carboxamideHCID 29798917—
Reactant4-Chloro-6-methyl-2-(methylthio)pyrimidine-5-carbonitrileHCID 58296308—
ProductN-(3-{[5-cyano-6-methyl-2-(methylthio)-4-pyrimidinyl]amino}phenyl)-1-pyrrolidinecarboxamideHCID 58296302—

Reaction Steps

The compound was prepared from 4-chloro-6-methyl-2-(methylthio)-5-pyrimidinecarbonitrile and N-(3-aminophenyl)-1-pyrrolidinecarboxamide following a procedure similar to that described for Intermediate 23.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08383635B2
Source datasetuspto-grants-2013_02
ORD IDord-ea962f0e72cc430ca4803b3df64d52da
Source noteuspto-grants-2013_02