Back
HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 390061Generated: October 25, 2026

N-(4-aminophenyl)-1-pyrrolidinecarboxamide → N-(4-{[5-cyano-6-methyl-2-(methylthio)-4-pyrimidinyl]amino}phenyl)-1-pyrrolidinecarboxamide

https://huagongshe.com/reaction/390061

Reaction equation

Participants

RoleNameHCIDCharge
ReactantN-(4-aminophenyl)-1-pyrrolidinecarboxamideHCID 43468894—
Reactant4-Chloro-6-methyl-2-(methylthio)pyrimidine-5-carbonitrileHCID 58296308—
ProductN-(4-{[5-cyano-6-methyl-2-(methylthio)-4-pyrimidinyl]amino}phenyl)-1-pyrrolidinecarboxamideHCID 67222311—

Reaction Steps

The compound was prepared from 4-chloro-6-methyl-2-(methylthio)-5-pyrimidinecarbonitrile and N-(4-aminophenyl)-1-pyrrolidinecarboxamide following procedure similar to that described for Intermediate 23.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08383635B2
Source datasetuspto-grants-2013_02
ORD IDord-7b36ea829e2f41b080754292656f10a8
Source noteuspto-grants-2013_02