反应详情

The title compound was prepared employing a procedure analogous to that described in Example 1 using methyl 2-(7-chloro-2,3-dihydrospiro[indene-1,4′-piperidine]-3-yl)acetate and 2,3-dichlorocinnamic acid followed by a procedure analogous to that described in Example 2. LC-MS Method 1 tR=1.98, min, m/z=480; 1H NMR (CDCl3) 1.52 (d, 2H), 1.71 (m, 2H), 2.40 (m, 1H), 2.49 (m, 1H), 2.65-3.10 (4H), 3.32 (m, 1H), 3.62 (m, 1H), 4.13 (d, 1H), 4.79 d, 1H), 6.88 (d, 1H), 7.05-7.30 (4H), 7.46 (d, 1H), 7.52 (d, 1H), 8.00 (d, 1H).