反应详情

The title compound was prepared following a procedure analogous to that described in Example 31 using 2-(2-(trifluoromethyl)phenyl)acetic acid and 7-bromospiro[isoindoline-1,4′-piperidin]-3-one. LC-MS Method 2 tR=2.092, min, m/z=469; 1H NMR (CDCl3) 1.35 (d, 1H), 1.43 (d, 1H), 2.72 (m, 1H), 2.90 (m, 2H), 3.40 (t, 1H), 3.80-4.05 (m, 3H), 4.88 (d, 1H), 7.31 (t, 2H), 7.38 (d, 1H), 7.48 (t, 1H), 7.61 (d, 1H), 7.68 (d, 1H), 7.78 (d, 1H), 9.17 (s, 1H).