HuagongsheHuagongshe Chemistry Print Report · For research reference only
4-Chloro-2-(trifluoromethyl)phenylacetic acid → 2-(7-Chloro-1'(2-(4-chloro-2-(trifluoromethyl)phenyl)acetyl)-2,3-dihydrospiro[indene-1,4'-piperidine]-3-yl)acetic acid
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 4-Chloro-2-(trifluoromethyl)phenylacetic acid | HCID 3277747 | — |
| Reactant | Ethyl 2-(7-chloro-2,3-dihydrospiro[indene-1,4'-piperidine]-3-yl)acetate | HCID 67224803 | — |
| Product | 2-(7-Chloro-1'(2-(4-chloro-2-(trifluoromethyl)phenyl)acetyl)-2,3-dihydrospiro[indene-1,4'-piperidine]-3-yl)acetic acid | HCID 58295669 | — |
Reaction Steps
The title compound was prepared following a procedure analogous to that described in Example 1 using 2-(4-chloro-2-(trifluoromethyl)phenyl)acetic acid and ethyl 2-(7-chloro-2,3-dihydrospiro[indene-1,4′-piperidine]-3-yl)acetate. LC-MS Method 1 tR=2.00, min, m/z=500.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08383629B2 |
| Source dataset | uspto-grants-2013_02 |
| ORD ID | ord-8d12fd4e9313469bad3a7d3cf08a36cb |
| Source note | uspto-grants-2013_02 |