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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 390182Generated: October 29, 2026

2-(Trifluoromethyl)benzenepropanoic acid → Ethyl 2-(7-bromo-1'-(3-(2-(trifluoromethyl)phenyl)propanoyl)-2,3-dihydrospiro[indene-1,4'-piperidine]-3-yl)acetate

https://huagongshe.com/reaction/390182

Reaction equation

Participants

RoleNameHCIDCharge
Reactant2-(Trifluoromethyl)benzenepropanoic acidHCID 15284809—
ReactantEthyl 2-(7-bromo-2,3-dihydrospiro[indene-1,4'-piperidine]-3-yl)acetateHCID 58137336—
ProductEthyl 2-(7-bromo-1'-(3-(2-(trifluoromethyl)phenyl)propanoyl)-2,3-dihydrospiro[indene-1,4'-piperidine]-3-yl)acetateHCID 58295705—

Reaction Steps

The title compound was prepared following a procedure analogous to that described in Example 1 using 3-(2-(trifluoromethyl)phenyl)propanoic acid and ethyl 2-(7-bromo-2,3-dihydrospiro[indene-1,4′-piperidine]-3-yl)acetate. LC-MS Method 1 tR=2.27, min, m/z=554, 552

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08383629B2
Source datasetuspto-grants-2013_02
ORD IDord-0e3245ab81e2401a94a1424282958a17
Source noteuspto-grants-2013_02