HuagongsheHuagongshe Chemistry Print Report · For research reference only
3-(2-Chlorophenyl)propanoic acid → 2-(7-Chloro-1'-(3-(2-chlorophenyl)propanoyl)-2,3-dihydrospiro[indene-1,4'-piperidine]-3-yl)acetic acid
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 3-(2-Chlorophenyl)propanoic acid | HCID 95676 | — |
| Reactant | Ethyl 2-(7-chloro-2,3-dihydrospiro[indene-1,4'-piperidine]-3-yl)acetate | HCID 67224803 | — |
| Product | 2-(7-Chloro-1'-(3-(2-chlorophenyl)propanoyl)-2,3-dihydrospiro[indene-1,4'-piperidine]-3-yl)acetic acid | HCID 58295673 | — |
Reaction Steps
The title compound was prepared following a procedure analogous to that described in Example 1 using 3-(2-chlorophenyl)propanoic acid and ethyl 2-(7-chloro-2,3-dihydrospiro[indene-1,4′-piperidine]-3-yl)acetate followed by a procedure analogous to that in Example 2. LC-MS Method 1 tR=1.87, min, m/z=446
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08383629B2 |
| Source dataset | uspto-grants-2013_02 |
| ORD ID | ord-303b22150aca4edc9c24f486f8152fec |
| Source note | uspto-grants-2013_02 |