反应详情

A mixture of 5-benzoyl-2-nitrobenzaldehyde (0.01 mol) in toluene was hydrogenated at room temperature and normal pressure with 5% Pd/C (2 g) as a catalyst in the presence of 4% thiophene solution (2 mL). After uptake of H2 gas (3 equiv.), the catalyst was filtered off and the filtrate was evaporated (water bath at 50° C.). The residue was dissolved in diethyl ether (10 mL) and crystallized out at room temperature. The crystals were filtered off, washed with a small amount of diethyl ether and diisopropyl ether, then dried (vacuum, 40° C.) to yield the title compound as a solid.

1. customwas hydrogenated at room temperature
2. filtrationAfter uptake of H2 gas (3 equiv.), the catalyst was filtered off
3. customthe filtrate was evaporated (water bath at 50° C.)
4. dissolutionThe residue was dissolved in diethyl ether (10 mL)
5. customcrystallized out at room temperature
6. filtrationThe crystals were filtered off
7. washwashed with a small amount of diethyl ether and diisopropyl ether
8. customdried (vacuum, 40° C.)