HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 390280Generated: October 28, 2026
Benzenesulfonyl chloride → HCID 58625117, compound
https://huagongshe.com/reaction/390280
Participants
| Role | Name | HCID | Charge |
|---|
| Reactant | Benzenesulfonyl chloride | HCID 7369 | — |
| Reactant | 3-(3-Dimethoxymethyl-4-nitro-phenylsulfanyl)-phenylamine | HCID 58625054 | — |
| Solvent | Tetrahydrofuran | HCID 8028 | — |
| Product | HCID 58625117 | HCID 58625117 | — |
Reaction Steps
A mixture of 3-(3-dimethoxymethyl-4-nitro-phenylsulfanyl)-phenylamine (0.0384 mol) and TEA (0.0578 mol) in THF (q.s.) was cooled to 5° C., and phenylsulfonyl chloride (0.0384 mol) was added dropwise at 5° C. Then, the reaction mixture was reacted at room temperature, and purified by column chromatography over silica gel (eluent: CH2Cl2). The product fractions were collected and the solvent was evaporated to yield the title compound as a residue.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|
| Patent number | US08383637B2 |
|---|
| Source dataset | uspto-grants-2013_02 |
|---|
| ORD ID | ord-d9d67f8bd7d14e169d983c216dad0092 |
|---|
| Source note | uspto-grants-2013_02 |
|---|
