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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 390319Generated: October 26, 2026

2-Methyl-1-nitronaphthalene → HCID 67235893, compound

https://huagongshe.com/reaction/390319

Reaction equation

Participants

RoleNameHCIDCharge
Reactant2-Methyl-1-nitronaphthaleneHCID 13432—
ReactantStyrylboronic acidHCID 5702628—
ReactantPotassium vinyltrifluoroborateHCID 23679353—
ReactantMethyl 1-amino-4-bromonaphthalene-2-carboxylateHCID 58431835—
ProductHCID 67235893HCID 67235893—

Reaction Steps

Methyl 5-amino-8-bromoisoquinoline-6-carboxylate was prepared by the procedure described for the synthesis of methyl 1-amino-4-bromo-2-naphthoate in Example 1, substituting 6-methyl-5-nitroisoquinoline for 2-methyl-1-nitronaphthalene and substituting [(E-2-phenylethenyl]boronic acid for potassium vinyltrifluoroborate.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08383638B2
Source datasetuspto-grants-2013_02
ORD IDord-b4e3a413cc954621bc6afd843efa703f
Source noteuspto-grants-2013_02