Hydroxylamine → HCID 178510821, compound

Participants

Reaction Steps

A solution of 2-(4-fluorophenyl)acetonitrile (1.35 g, 10 mmol) and 50% aq. hydroxylamine (1.33 g, 20 mmol) in EtOH (10 mL) was stirred at 90° C. for 18 h then cooled and concentrated to afford the title compound (1.68 g, 100% yield) as white solid. 1HNMR (500 MHz, CDCl3) δ: 8.04-7.85 (1H, br s), 7.24 (2H, dd, J=8.6, 5.5 Hz), 7.01 (2H, t, J=8.6 Hz), 4.46 (2H, s), 3.43 (2H, s). LCMS (M+H): 169.14.

Provenance & Evidence