Methane → HCID 58066686, compound

Participants

Reaction Conditions

Reaction Steps

2-tert-Butylsulfanylmethyl-4-nitro-benzoic acid methyl ester (5.68 g, 19.1 mmol), 1,1-dimethylhydrazine (11.6 mL, 192 mmol), and DARCO (2.0 g, 19.1 mmol) were combined in MeOH (200 mL). Ferric chloride (0.50 g, 3.1 mmol) was added, and the reaction was stirred at 70° C. for 3.5 hours. The mixture was stored in the freezer overnight, and then worked-up and purified by silica gel chromatography to give the title compound.

Provenance & Evidence