Ammonia → HCID 44546283, compound

HRID 390453Notes

Reaction equation

HRID 390453 reaction equation
[OH:1][N:2]=[C:3](Cl)[C:4]1[CH:9]=[CH:8][CH:7]=[N:6][CH:5]=1.[C:11]([C:13]1[CH:18]=[CH:17][C:16]([CH3:19])=[CH:15][CH:14]=1)#[CH:12].N>>[N:6]1[CH:7]=[CH:8][CH:9]=[C:4]([C:3]2[CH:12]=[C:11]([C:13]3[CH:18]=[CH:17][C:16]([CH3:19])=[CH:15][CH:14]=3)[O:1][N:2]=2)[CH:5]=1

Participants

4

Reactant 3

HCID 222AmmoniaHCID 13018p-EthynyltolueneHCID 53404818N-Hydroxy-3-pyridinecarboximidoyl chloride

Product 1

HCID 44546283HCID 44546283, compound

Procedure

The titled compound was prepared according to Method CB using the product of Example 1A (78 mg, 0.5 mmol) and 1-ethynyl-4-methylbenzene (Apollo, 58 mg, 0.5 mmol). 1H NMR (300 MHz, MeOH-d4) δ 2.43 (s, 3H), 7.30 (s, 1H), 7.36 (d, J=7.8 Hz, 2H), 7.60 (dd, J=7.6, 4.6 Hz, 1H), 7.81 (d, J=8.5 Hz, 2H), 8.36 (dt, J=8.2, 1.8 Hz, 1H), 8.66 (dd, J=4.9, 1.5 Hz, 1H), 9.09 (d, J=3.1 Hz, 1H) ppm; MS (DCI/NH3) m/z 237 (M+H)+.

Sources & evidence

ORD record
ord-6fd1d544b9d84588a0cde72f93ae34d3
Source dataset
uspto-grants-2013_02
Patent number
US08383658B2

Reaction notes

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