反应详情

The titled compound was prepared according to Method CB using the product of Example 28B (88 mg, 0.5 mmol) and 1,2-dichloro-4-ethynylbenzene (Aldrich, 86 mg, 0.5 mmol). 1H NMR (300 MHz, MeOH-d4) δ 7.50 (s, 1H), 7.72 (d, J=8.3 Hz 1H), 7.86 (dd, J=8.3, 1.9 Hz 1H), 8.12 (d, J=2.0 Hz, 1H), 8.17 (ddd, J=9.1, 2.8, 1.6 Hz, 1H), 8.62 (d, J=2.8 Hz, 1H), 8.97 (t, J=1.4 Hz, 1H) ppm; MS (DCI/NH3) m/z 311 (M+H)+, 309 (M+H)+.