反应详情

The target product 17-cyclohexyl-18-[4-[2-morpholin-4-yl-5-(2-oxo-pyrrolidin-1-yl)-benzyloxy]-phenyl]-1,4,11-triaza-tricyclo[11.5.2.016,19]icosa-7,13 (20),14,16(19),17-pentaene-3,12-dione 11 was synthesized in 25% yield, following the procedure reported for the synthesis of compound 3 and using intermediate 10-11 instead of intermediate 3-11; m/z=730 (M+H)+.