HuagongsheHuagongshe Chemistry Print Report · For research reference only
Ammonia → HCID 44546481, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Ammonia | HCID 222 | — |
| Reactant | Benzene, 1-chloro-4-ethynyl- | HCID 70118 | — |
| Reactant | N-Hydroxypyrimidine-5-carbimidoyl chloride | HCID 86636847 | — |
| Product | HCID 44546481 | HCID 44546481 | — |
Reaction Steps
The titled compound was prepared as the hydrochloride salt according to Method CB using the product of Example 44B (79 mg, 0.5 mmol) and 1-chloro-4-ethynylbenzene (Aldrich, 68 mg, 0.5 mmol). 1H NMR (300 MHz, DMSO-d6) δ 7.69 (dt, J=9.0, 2.3, Hz, 2H), 7.82 (s, 1H), 7.94 (dt, J=9.0, 2.4 Hz, 2H), 9.32 (s, 2H), 9.35 (s, 1H) ppm; MS (DCI/NH3) m/z 260 (M+H)+, 258 (M+H)+.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08383658B2 |
| Source dataset | uspto-grants-2013_02 |
| ORD ID | ord-9f37fb10926946448e1291547a7ed9b6 |
| Source note | uspto-grants-2013_02 |