HuagongsheHuagongshe Chemistry Print Report · For research reference only
Ammonia → HCID 44545545, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Ammonia | HCID 222 | — |
| Reactant | 1-Ethynyl-4-fluorobenzene | HCID 522627 | — |
| Reactant | 5-Chloro-N-hydroxynicotinimidoyl chloride | HCID 86636849 | — |
| Product | HCID 44545545 | HCID 44545545 | — |
Reaction Steps
The titled compound was prepared according to Method CB using the product of Example 69B (57 mg, 0.3 mmol) and 1-ethynyl-4-fluorobenzene (Aldrich, 36 mg, 0.3 mmol). 1H NMR (300 MHz, DMSO-d6) δ 7.41-7.57 (m, 2H), 7.76 (s, 1H), 7.90-8.05 (m, 2H), 8.43 (t, J=2.2 Hz, 1H), 8.80 (d, J=2.4 Hz, 1H), 9.08 (d, J=1.6 Hz, 1H) ppm; MS (DCI/NH3) m/z 275 (M+H)+, 277 (M+H)+.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08383658B2 |
| Source dataset | uspto-grants-2013_02 |
| ORD ID | ord-594ff037e0384aa58d8ca670d93de0d7 |
| Source note | uspto-grants-2013_02 |