HuagongsheHuagongshe Chemistry Print Report · For research reference only
Ammonia → HCID 44545611, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Ammonia | HCID 222 | — |
| Reactant | 3-Methylphenylacetylene | HCID 136600 | — |
| Reactant | 5-Chloro-N-hydroxynicotinimidoyl chloride | HCID 86636849 | — |
| Product | HCID 44545611 | HCID 44545611 | — |
Reaction Steps
The titled compound was prepared according to Method CB using the product of Example 69B (57 mg, 0.3 mmol) and 1-ethynyl-3-methylbenzene (Aldrich, 35 mg, 0.3 mmol). 1H NMR (300 MHz, DMSO-d6) δ 2.42 (s, 3H), 7.38 (d, J=7.5 Hz, 1H), 7.49 (t, J=7.6 Hz, 1H), 7.66-7.75 (m, 2H), 7.75 (s, 1H), 8.44 (t, J=2.1 Hz, 1 H), 8.80 (d, J=2.4 Hz, 1H), 9.09 (d, J=2.0 Hz, 1H) ppm; MS (DCI/NH3) m/z 271 (M+H)+, 273 (M+H)+.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08383658B2 |
| Source dataset | uspto-grants-2013_02 |
| ORD ID | ord-3525d7e3120f4dbbad69b8c3d2c5d03e |
| Source note | uspto-grants-2013_02 |