HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 390539Generated: October 28, 2026
Chlorosuccinimide → HCID 178478425, compound
https://huagongshe.com/reaction/390539
Participants
| Role | Name | HCID | Charge |
|---|
| Reactant | Chlorosuccinimide | HCID 31398 | — |
| Reactant | 1H-pyrazolo(3,4-b)pyridine | HCID 2755850 | — |
| Solvent | Dichloromethane | HCID 6344 | — |
| Product | HCID 178478425 | HCID 178478425 | — |
Reaction Steps
1H-pyrazolo[3,4-b]pyridine (89 mg) and N-chlorosuccinimide (220 mg) were combined in CH2Cl2 (4 mL) and heated at 45° C. for 16 hr, then cooled to room temperature. The resultant mixture was purified by flash chromatography (silica gel, 50% hexane/ethyl acetate) to afford 3-chloro-1H-pyrazolo[3,4-b]pyridine.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
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| Patent number | US08383630B2 |
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| Source dataset | uspto-grants-2013_02 |
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| ORD ID | ord-8f0e0f1639f049a09fd9ac30eb918019 |
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| Source note | uspto-grants-2013_02 |
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