Cyclohexylamine → ethyl (Z)-3-[3'-(3-cyclohexyl-1-methylureido)biphenyl-4-yl]-2-ethoxyacrylate

Participants

Reaction Steps

In a manner similar to that of Example 43d, starting with 1.75 g (3 mmol) of ethyl (Z)-2-ethoxy-3-{3′-[methyl(4-nitrophenoxycarbonyl)amino]biphenyl-4-yl}acrylate (prepared according to Example 43c) and 0.42 mL (3.7 mmol) of cyclohexylamine, 0.7 g (50%) of ethyl (Z)-3-[3′-(3-cyclohexyl-1-methylureido)biphenyl-4-yl]-2-ethoxyacrylate is obtained.

Provenance & Evidence