n-Heptyl isocyanate → methyl (Z)-3-[2-butoxy-3'-(3-heptylureido)biphenyl-4-yl]-2-methoxyacrylate

Participants

Reaction Steps

376 mg (1.1 mmol) of methyl (Z)-3-(3′-amino-2-butoxybiphenyl-4-yl)-2-methoxyacrylate and 0.3 mL (2.2 mmol) of heptyl isocyanate are heated at 100° C. by microwave in an Emrys Optimizer machine for 20 minutes. The residue obtained is taken up in ether and then filtered by suction. 431 mg (79%) of methyl (Z)-3-[2-butoxy-3′-(3-heptylureido)biphenyl-4-yl]-2-methoxyacrylate are obtained in the form of a white powder.

Provenance & Evidence