HuagongsheHuagongshe Chemie-Druckbericht · Nur für Forschungszwecke
4-Methanesulfonylpiperidine hydrochloride → 2-Chloro-6-(4-methanesulfonyl-piperidin-1-ylmethyl)-4-morpholin-4-yl-thieno[3,2-d]pyrimidine
Beteiligte Stoffe
| Rolle | Name | HCID | Einwaage |
|---|---|---|---|
| Edukt | 4-Methanesulfonylpiperidine hydrochloride | HCID 23061698 | — |
| Edukt | 2-Chloro-4-morpholinothieno[3,2-d]pyrimidine-6-carbaldehyde | HCID 45789985 | — |
| Produkt | 2-Chloro-6-(4-methanesulfonyl-piperidin-1-ylmethyl)-4-morpholin-4-yl-thieno[3,2-d]pyrimidine | HCID 57494044 | — |
Reaktionsschritte
4-Methanesulfonyl-piperidine hydrochloride salt was reacted with 2-chloro-4-morpholin-4-yl-thieno[3,2-d]pyrimidine-6-carbaldehyde 10 following General Procedure B-3. Purification on silica yielded 2-chloro-6-(4-methanesulfonyl-piperidin-1-ylmethyl)-4-morpholin-4-yl-thieno[3,2-d]pyrimidine.
Herkunft & Nachweise
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patentnummer | US08383620B2 |
| Quelldatensatz | uspto-grants-2013_02 |
| ORD ID | ord-3797cb5633bb4eb18a592d26c8e0d749 |
| Quellennotiz | uspto-grants-2013_02 |