HRID390903

反应详情

EQUATION

反应方程式

REACTANTS

反应物

HCID17998987

5-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)pyrazin-2-amine

C10H16BN3O2

结构：CS(=O)(=O)N1CCN(Cc2cc3nc(Cl)nc(N4CCOCC4)c3s2)CC1

HCID23650837

2-Chloro-6-{[4-(methanesulfonyl)piperazin-1-yl]methyl}-4-(morpholin-4-yl)thieno[3,2-d]pyrimidine

C16H22ClN5O3S2

PRODUCTS

生成物

结构：Nc1cnc(-c2nc(N3CCOCC3)c3sc(CN4CCNCC4)cc3n2)cn1

HCID66934007

未命名化合物

PROCEDURE

实验过程

2-Chloro-6-((4-methanesulfonylpiperazin-1-yl)methyl)-4-morpholinothieno[3,2-d]pyrimidine (75 mg) was reacted with 5-aminopyrazine-2-boronic acid pinacol ester following General Procedure A to give 20 mg of 187 following reversed phase HPLC purification. MS (Q1) 491 (M)+