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HRID390943

反应详情

EQUATION

反应方程式

HRID 390943 的结构方程式

REACTANTS

反应物

2
结构：CC1(C)OB(c2cncc(C=O)c2)OC1(C)C
HCID4992640

5-Formylpyridine-3-boronic acid pinacol ester

C12H16BNO3

结构：CS(=O)(=O)N1CCN(Cc2cc3nc(Cl)nc(N4CCOCC4)c3o2)CC1
HCID56833744

未命名化合物

PRODUCTS

生成物

1
结构：CS(=O)(=O)N1CCN(Cc2cc3nc(-c4cncc(C=O)c4)nc(N4CCOCC4)c3o2)CC1
HCID58234012

未命名化合物

PROCEDURE

实验过程

2-Chloro-6-((4-(methylsulfonyl)piperazin-1-yl)methyl)-4-morpholinofuro[3,2-d]pyrimidine (Example 153) was reacted with 5-(4,4,5,5-tetramethyl-[1,3,2]dioxaborolan-2-yl)-pyridine-3-carbaldehyde via General Procedure E to give, after purification by reverse HPLC, 11 mg of 238. MS (Q1) 487 (M+).

WORKUP

后处理

  1. customto give
  2. customafter purification by reverse HPLC, 11 mg of 238