HuagongsheHuagongshe Chemistry Print Report · For research reference only
n,n-Dimethylpiperazine-1-carboxamide → 4-((2-chloro-4-morpholinothieno[2,3-d]pyrimidin-6-yl)methyl)-N,N-dimethylpiperazine-1-carboxamide
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | n,n-Dimethylpiperazine-1-carboxamide | HCID 712909 | — |
| Reactant | 2-Chloro-4-morpholinothieno[2,3-d]pyrimidine-6-carbaldehyde | HCID 56833844 | — |
| Product | 4-((2-chloro-4-morpholinothieno[2,3-d]pyrimidin-6-yl)methyl)-N,N-dimethylpiperazine-1-carboxamide | HCID 56834051 | — |
Reaction Steps
Reaction between 2-chloro-4-morpholin-4-yl-thieno[2,3-d]pyrimidine-6-carbaldehyde (General Procedure D-2) and piperazine-1-carboxylic acid dimethylamide (Example 26) using General Procedure B-3 yielded 4-((2-chloro-4-morpholinothieno[2,3-d]pyrimidin-6-yl)methyl)-N,N-dimethylpiperazine-1-carboxamide.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08383620B2 |
| Source dataset | uspto-grants-2013_02 |
| ORD ID | ord-8e3ea463fb524606916ac23f9a309103 |
| Source note | uspto-grants-2013_02 |