HuagongsheHuagongshe Chemistry Print Report · For research reference only
4-(Methanesulfonyl)piperidine → 2-Chloro-6-(4-methanesulfonyl-piperidin-1-ylmethyl)-4-morpholin-4-yl-thieno[2,3-d]pyrimidine
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 4-(Methanesulfonyl)piperidine | HCID 22275038 | — |
| Reactant | 2-Chloro-4-morpholinothieno[2,3-d]pyrimidine-6-carbaldehyde | HCID 56833844 | — |
| Product | 2-Chloro-6-(4-methanesulfonyl-piperidin-1-ylmethyl)-4-morpholin-4-yl-thieno[2,3-d]pyrimidine | HCID 86623538 | — |
Reaction Steps
Reaction between 2-chloro-4-morpholin-4-yl-thieno[2,3-d]pyrimidine-6-carbaldehyde (General Procedure D-2) and 4-methanesulfonyl-piperidine (Example 34) using General Procedure B-3 yielded 2-chloro-6-(4-methanesulfonyl-piperidin-1-ylmethyl)-4-morpholin-4-yl-thieno[2,3-d]pyrimidine.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08383620B2 |
| Source dataset | uspto-grants-2013_02 |
| ORD ID | ord-539341d2bdb542a9a22dbee66b7b4645 |
| Source note | uspto-grants-2013_02 |