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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 391103Generated: October 31, 2026

Trifluoroacetic acid → HCID 58233970, compound

https://huagongshe.com/reaction/391103

Reaction equation

Participants

RoleNameHCIDCharge
ReactantTrifluoroacetic acidHCID 6422—
ReactantL-Lactic AcidHCID 107689—
ReactantHCID 66934078HCID 66934078—
ProductHCID 58233970HCID 58233970—

Reaction Steps

The crude TFA salt of N-methyl-5-(4-morpholino-6-((piperazin-1-yl)methyl)thieno[2,3-d]pyrimidin-2-yl)pyrimidin-2-amine was reacted with L-lactic acid via General Procedure B to give 28.3 mg of 388 after reverse phase HPLC purification. MS (Q1) 499.3 (M)+

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08383620B2
Source datasetuspto-grants-2013_02
ORD IDord-9e3991fc6b374730bd3b372b9d0d5ee2
Source noteuspto-grants-2013_02