HuagongsheHuagongshe Chemistry Print Report · For research reference only
Citric Acid → Promethazine
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Citric Acid | HCID 311 | — |
| Reactant | Sucrose | HCID 5988 | — |
| Reactant | Promethazine Hydrochloride | HCID 6014 | — |
| Reactant | N-vinyl-2-pyrrolidone | HCID 6917 | — |
| Reactant | Sorbic Acid | HCID 643460 | — |
| Solvent | Water | HCID 962 | — |
| Product | Promethazine | HCID 4927 | — |
Reaction Steps
22.6 g of promethazine HCl, 25.0 g of polyvinylpyrrolidone K 90 prepared as in Example 8, 5.0 g of citric acid, 2.0 g of sorbic acid and 60.0 g of sucrose were dissolved in 975.0 g of demineralized water at 50° C., and the solution was cooled to room temperature and dispensed into 50 ml amber glass bottles.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08524827B2 |
| Source dataset | uspto-grants-2013_09 |
| ORD ID | ord-ee649061a5d1459fbcf89e3caa807012 |
| Source note | uspto-grants-2013_09 |