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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 391211Generated: October 27, 2026

Ethyl 3-hydroxybenzoate → 3-((5-Chloropyridin-2-yl)oxy)benzoic acid

https://huagongshe.com/reaction/391211

Reaction equation

Participants

RoleNameHCIDCharge
ReactantEthyl 3-hydroxybenzoateHCID 24522—
Reactant2,5-DichloropyridineHCID 27685—
Product3-((5-Chloropyridin-2-yl)oxy)benzoic acidHCID 61395583—

Reaction Steps

Prepared from 2,5-dichloropyridine and ethyl 3-hydroxybenzoate. 1H NMR (400 MHz, DMSO-d6) δ 13.17 (br. s., 1 H), 8.22 (d, 1 H), 8.00 (dd, 1 H), 7.81 (dd, 1 H), 7.60-7.64 (m, 1 H), 7.58 (t, 1 H), 7.43 (dd, 1 H), 7.18 (d, 1 H).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08383820B2
Source datasetuspto-grants-2013_02
ORD IDord-3cc5fdfb462e48bebd62336283c74ed8
Source noteuspto-grants-2013_02