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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 391226Generated: October 26, 2026

4-Aminoadamantan-1-ol → 3-(5-Chloro-pyridin-2-yloxy)-N-(5-hydroxy-adamantan-2-yl)-benzamide

https://huagongshe.com/reaction/391226

Reaction equation

Participants

RoleNameHCIDCharge
Reactant4-Aminoadamantan-1-olHCID 2857447—
Reactant3-((5-Chloropyridin-2-yl)oxy)benzoic acidHCID 61395583—
Product3-(5-Chloro-pyridin-2-yloxy)-N-(5-hydroxy-adamantan-2-yl)-benzamideHCID 46196351—

Reaction Steps

Prepared from 3-(5-chloro-pyridin-2-yloxy)-benzoic acid and 4-amino-1-hydroxyadamantane. 1H NMR (400 MHz, CDCl3): δ 8.11 (s, 1 H), 7.68 (d, 1 H), 7.51-7.61 (m, 2 H), 7.47 (t, 1 H), 6.94 (d, 1 H), 6.23-6.36 (m, 1 H), 4.08-4.25 (m, 1 H), 2.24 (t, 3 H), 1.51-2.03 (m, 13 H).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08383820B2
Source datasetuspto-grants-2013_02
ORD IDord-0a5c15911c06484a959237c0d8d982e0
Source noteuspto-grants-2013_02