Water → HCID 58479943, compound

HRID 391499Notes

Reaction equation

HRID 391499 reaction equation
[Br:1][C:2]1[CH:3]=[C:4]([CH:7]=[C:8]([Br:10])[CH:9]=1)[CH:5]=O.[NH2:11][C:12]1[CH:17]=[CH:16][CH:15]=[CH:14][C:13]=1[SH:18].C([O-])(=O)C.[Pb+4].C([O-])(=O)C.C([O-])(=O)C.C([O-])(=O)C.O>C(O)(=O)C>[Br:1][C:2]1[CH:3]=[C:4]([C:5]2[S:18][C:13]3[CH:14]=[CH:15][CH:16]=[CH:17][C:12]=3[N:11]=2)[CH:7]=[C:8]([Br:10])[CH:9]=1

Participants

6

Reactant 4

HCID 962WaterHCID 87132-AminothiophenolHCID 6220773,5-DibromobenzaldehydeHCID 178418268HCID 178418268, compound

Product 1

HCID 58479943HCID 58479943, compound

Reagents, catalysts & solvents 1

HCID 176Acetic AcidSolvent

Procedure

5.03 g (19.1 mmol) of 3,5-dibromobenzaldehyde and 3.1 mL (28.6 mmol) of 2-aminothiophenol were dissolved in 60 mL of acetic acid. The solution was agitated at room temperature for 30 minutes. 9.78 g (21.0 mmol) of lead (IV) acetate was added thereto. The resulting mixture was agitated at 50° C. for 1 hour. Then, water was poured into the reactant. It was extracted with ethyl acetate. The extract was separated through a column and dried, obtaining 4.74 g (Y=67%) of a white solid.

Workup

  1. stirringThe resulting mixture was agitated at 50° C. for 1 hour
  2. extractionIt was extracted with ethyl acetate
  3. customThe extract was separated through a column
  4. customdried
  5. customobtaining 4.74 g (Y=67%) of a white solid

Sources & evidence

ORD record
ord-d12e3e08e91a44c4b432ea168b810d9d
Source dataset
uspto-grants-2013_02
Patent number
US08383932B2

Reaction notes

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