反应详情

6.58 g (34.0 mmol) of 2-bromo-3-pyrdinecarboxaldehyde and 5.5 mL (50.9 mmol) of 2-aminothiophenol were dissolved in 150 mL of acetic acid. The solution was agitated at room temperature for 30 minutes. Next, 19.0 g (40.8 mmol) of lead (IV) acetate was added thereto. The resulting product was agitated at 50° C. for 1 hour. Then, water was added to the acquired reactant. The mixture was extracted with ethyl acetate and treated under reduced pressure to remove the solvent, obtaining 5.55 g (Y=55%) of a white solid.

1. stirringThe resulting product was agitated at 50° C. for 1 hour
2. extractionThe mixture was extracted with ethyl acetate
3. additiontreated under reduced pressure
4. customto remove the solvent
5. customobtaining 5.55 g (Y=55%) of a white solid