4-Iodopyrazole → HCID 24954547, compound

HRID 391531Notes

Reaction equation

HRID 391531 reaction equation
[C:1]([C:3]1[CH:4]=[N:5][CH:6]=[C:7]([CH:20]=1)[C:8]([N:10]=[S@@:11]([CH3:19])(=[O:18])[C:12]1[CH:17]=[CH:16][CH:15]=[CH:14][CH:13]=1)=[O:9])#[CH:2].I[C:22]1[CH:23]=[N:24][NH:25][CH:26]=1>>[CH3:19][S@:11](=[O:18])([C:12]1[CH:13]=[CH:14][CH:15]=[CH:16][CH:17]=1)=[N:10][C:8](=[O:9])[C:7]1[CH:20]=[C:3]([C:1]#[C:2][C:22]2[CH:23]=[N:24][NH:25][CH:26]=2)[CH:4]=[N:5][CH:6]=1

Participants

3

Reactant 2

HCID 770224-IodopyrazoleHCID 24953136(S)-5-ethynyl-N-[methyl(oxo)phenyl-lambda6-sulfanylidene]nicotinamide

Product 1

HCID 24954547HCID 24954547, compound

Procedure

In a manner similar to that describe in Example 431 a mixture of (S)-5-ethynyl-N—[methyl(oxo)phenyl-λ6-sulfanylidene]nicotinamide and 4-iodopyrazole were reacted to give the title compound as a white film (15 mg, 17%).

Workup

  1. customwere reacted

Sources & evidence

ORD record
ord-0098f604872541aa9e4c79b0cb3b5a3c
Source dataset
uspto-grants-2013_02
Patent number
US08383825B2

Reaction notes

Loading…