HuagongsheHuagongshe Chemistry Print Report · For research reference only
Potassium Carbonate → Methyl 3-[4-(S-methylsulfonimidoyl)phenyl]propanoate
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Potassium Carbonate | HCID 11430 | — |
| Reactant | Methyl 3-{4-[S-methyl-N-(trifluoroacetyl)sulfonimidoyl]phenyl}-propanoate | HCID 57657821 | — |
| Solvent | Methanol | HCID 887 | — |
| Product | Methyl 3-[4-(S-methylsulfonimidoyl)phenyl]propanoate | HCID 57657822 | 93.3% |
Reaction Steps
Methyl 3-{4-[S-methyl-N-(trifluoroacetyl)sulfonimidoyl]phenyl}propanoate (0.200 g, 0.653 mmol) was dissolved in MeOH (3 mL). K2CO3 (0.450 g, 3.27 mmol) was added to the solution, and the resulting suspension was allowed to stir for 5 minutes. The suspension was filtered and the filtrate was concentrated. The residue was dissolved in EtOAc and dried over anhydrous anhydrous Na2SO4(s) to give the title compound (0.147 g, 93%).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08383825B2 |
| Source dataset | uspto-grants-2013_02 |
| ORD ID | ord-51dab07d77ba41a885011de6cd0223f2 |
| Source note | uspto-grants-2013_02 |