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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 391605Generated: October 29, 2026

Ethyl nipecotate → (S)-Ethyl 1-[(N-{[5-({3-[(3-methyl-2-furoyl)amino]phenyl}ethynyl)pyridin-3-yl]carbonyl}-S-phenylsulfonimidoyl)acetyl]piperidine-3-carboxylate

https://huagongshe.com/reaction/391605

Reaction equation

Participants

RoleNameHCIDCharge
ReactantEthyl nipecotateHCID 98969—
Reactant(S)-Ethyl (N-{[5-({3-[(3-methyl-2-furoyl)amino]phenyl}ethynyl)pyridin-3-yl]carbonyl}-S-phenylsulfonimidoyl)acetateHCID 57657941—
Product(S)-Ethyl 1-[(N-{[5-({3-[(3-methyl-2-furoyl)amino]phenyl}ethynyl)pyridin-3-yl]carbonyl}-S-phenylsulfonimidoyl)acetyl]piperidine-3-carboxylateHCID 86629491—

Reaction Steps

In a manner similar to that described in Example 534, (S)-Ethyl (N-{[5-({3-[(3-methyl-2-furoyl)amino]phenyl}ethynyl)pyridin-3-yl]carbonyl}-S-phenylsulfonimidoyl)acetate and ethyl nipecotate were reacted to give the title compound

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08383825B2
Source datasetuspto-grants-2013_02
ORD IDord-2e8475e681cd44e9b9b414b64174191d
Source noteuspto-grants-2013_02