Methyl{3-[s-methyl-n-(trifluoroacetyl)sulfonimidoyl]phenyl}acetate → methyl {3-[N-({6-amino-5-[(3-{[(1,3-dimethyl-1H-pyrazol-5-yl)carbonyl]amino}phenyl)ethynyl]pyridin-3-yl}carbonyl)-S-methylsulfonimidoyl]phenyl}acetate

Participants

Role	Name	HCID	Charge
Reactant	Methyl{3-[s-methyl-n-(trifluoroacetyl)sulfonimidoyl]phenyl}acetate	HCID 57657827	—
Reactant	6-Amino-5-{3-[(2,5-dimethyl-2H-pyrazole-3-carbonyl)-amino]-phenylethynyl}-nicotinic acid	HCID 57657867	—
Product	methyl {3-[N-({6-amino-5-[(3-{[(1,3-dimethyl-1H-pyrazol-5-yl)carbonyl]amino}phenyl)ethynyl]pyridin-3-yl}carbonyl)-S-methylsulfonimidoyl]phenyl}acetate	HCID 57657942	—

Reaction Steps

In a manner similar to that described in Example 496 (step 5), 6-amino-5-[(3-{[(1,3-dimethyl-1H-pyrazol-5-yl)carbonyl]amino}phenyl)ethynyl]nicotinic acid and methyl {3-[S-methyl-N-(trifluoroacetyl)sulfonimidoyl]phenyl}acetate were reacted to give the title compound

Provenance & Evidence

DOI	10.6084/m9.figshare.5104873.v1
Patent number	US08383825B2
Source dataset	uspto-grants-2013_02
ORD ID	ord-af840711d82e4d3bae944c1ed2dfb980
Source note	uspto-grants-2013_02