HuagongsheHuagongshe Chemistry Print Report · For research reference only
Methylamine → N,6-Dimethyl-5-nitropyridin-2-amine
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Methylamine | HCID 6329 | — |
| Reactant | 6-Chloro-2-methyl-3-nitropyridine | HCID 253123 | — |
| Product | N,6-Dimethyl-5-nitropyridin-2-amine | HCID 13567018 | — |
Reaction Steps
6-Chloro-2-methyl-3-nitro-pyridine (0.6 g) was treated with methyl amine according to General Procedure U to give methyl-(6-methyl-5-nitro-pyridin-2-yl)-amine LCMS (m/z): 168. This was reduced under hydrogen atmosphere according to General Procedure Z to give 6,N*2*-dimethyl-pyridine-2,5-diamine (0.35 g), LCMS (m/z): 138. This was converted to 2-methyl-6-methylamino-pyridine-3-sulfonyl chloride according to General Procedure AA.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08383644B2 |
| Source dataset | uspto-grants-2013_02 |
| ORD ID | ord-cef58ffa0e2c4e5eb7e4d5ca870feabc |
| Source note | uspto-grants-2013_02 |