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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 391883Generated: October 30, 2026

1,2-Pyrrolidinedicarboxylic acid, 1-(1,1-dimethylethyl) ester, (2S)- → HCID 86654914, compound

https://huagongshe.com/reaction/391883

Reaction equation

Participants

RoleNameHCIDCharge
Reactant1,2-Pyrrolidinedicarboxylic acid, 1-(1,1-dimethylethyl) ester, (2S)-HCID 85083—
ReactantHCID 86654897HCID 86654897—
ProductHCID 86654914HCID 86654914—

Reaction Steps

The title compound (18 mg) was prepared from (S)-2-({(S)-7-(2-Amino-4-methyl-thiazole-5-sulfonyl)-3-[4-(3,4-dichloro-benzyloxy)-phenyl]-2,3,6,7,8,9-hexahydro-[1,4]dioxino[2,3-g]isoquinoline-8-carbonyl}-amino)-3-(4′-cyano-biphenyl-4-yl)-propionic acid methyl ester and boc-L-proline according to General Procedures L, C, and B. LCMS (m/z): 1008.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08383644B2
Source datasetuspto-grants-2013_02
ORD IDord-267d4127b874415abb3c77dc8562f631
Source noteuspto-grants-2013_02